respiratory-care-blog-post

What is Respiratory Care: Trends and Advancements

Patients with severe respiratory disorders frequently require specialized care in the Intensive Care Unit (ICU), a vital area in healthcare. The field of respiratory care advances in tandem with medical science. The future of respiratory care is closely tied to virtual care technology. As we explore changes in respiratory health, it’s clear that new and improved virtual care solutions are shaping how we approach diagnosis and treatment.

This blog explores cutting-edge developments in respiratory care that have the potential to completely transform the way we diagnose, manage, and treat respiratory conditions.

ICU In The Context Of Respiratory Care

A cooperative team of medical experts, comprising doctors, nurses, and the vital respiratory therapist, collaborates in the dynamic Intensive Care Unit (ICU) to deliver unmatched care to patients in critical condition. Their proficiency encompasses various tasks, including complex ventilator control, diagnostic blood drawing, and bronchoscopy support. Specialized gas administration including treatments such as heliox and nitric oxide and careful attention to every aspect of hemodynamic monitoring highlight the respiratory therapist’s vital roles in this high-stakes setting. [1]

Respiratory Care Personalized Medicine

Personalized medicine is a cutting-edge approach that customizes medical treatments based on a person’s genetic composition, lifestyle, and surroundings. It refers to creating respiratory care plans specially tailored to every patient’s requirements. Pharmacogenomics, which identifies the safest and most effective drugs for specific patients, is one possible example. Genetic differences can affect a person’s response to a drug, so adjusting a medication’s dosage could significantly improve treatment results.

Wearable technology developments are crucial for real-time patient monitoring, respiratory pattern data collection, and individualized interventions or feedback. Intelligent inhalers, which track medication compliance and offer instantaneous feedback, are invaluable for treating respiratory ailments. Pulmonary function tests are easily accessible with portable electronic spirometers, which close the gap between patient monitoring and diagnosis. Furthermore, digital stethoscopes that use artificial intelligence (AI) improve lung auscultation accuracy and offer useful diagnostic information. [2]

Machine Learning and AI in Radiation Therapy

Significant progress is being made in changing respiratory care through artificial intelligence (AI) and machine learning (ML). These technologies are adept at analyzing vast datasets with unprecedented speed and accuracy, offering clinicians valuable insights for treatment planning and decision-making. They help optimize ventilator settings for individual patients to predictive analytics for early disease detection.

AI is a valuable tool in predicting disease progression, enabling medical professionals to customize treatment regimens and interventions to improve patient outcomes. By utilizing extensive biological and clinical datasets, these technologies provide priceless insights for forecasting outcomes, individualized treatment planning, and disease prediction. One prominent example is the application of AI algorithms to the analysis of medical imaging, including CT and chest X-rays, for the early diagnosis of respiratory disorders. Diagnoses can be made more quickly and accurately thanks to these systems’ ability to spot irregularities and subtle patterns that the human eye might miss. [3]

How does AI help respiratory medicine?

The revolutionary collaboration of AI, ML, and respiratory medicine advances our knowledge of disease mechanisms, expedites drug development, and improves personalized therapies.

AI helps: 

  • Diagnose and treat lung cancer
  • Evaluate fibrotic lung diseases
  • Interpret pulmonary function tests and manage COPD
  • Aids in prioritizing possible therapies
  • Predicting the structures of infectious proteins 
  • Drug discovery

Even with the encouraging results, cautious application of AI in clinical practice is still necessary due to data quality, validation, and ethical issues. [4]

AI & ML together facilitate adaptive treatment planning by continuously learning from patient responses, enabling dynamic adjustments to therapy regimens in real time.

Developments in Biotechnology: Gene Therapy, Stem Cells, and Regenerative Medicine

Gene therapy, leveraging the precision of genetic manipulation, holds the promise of treating and potentially curing a spectrum of genetic disorders by correcting or replacing faulty genes. Stem cell therapies use the regenerative power of versatile cells to repair and regenerate injured lung tissues.

Imagine a time when lung cell-regenerating therapies will be available to patients with chronic respiratory diseases, improving their overall quality of life and lung function. The swift advancement in stem cell research presents great potential for regenerative medicine. It highlights the potential uses of induced pluripotent stem cells (iPSCs) for the treatment of lung and liver diseases, with an emphasis on lung degeneration and Alpha-1 Antitrypsin Deficiency (A1AD). [5]

iPSCs are used to treat diseases like cancer, fibrosis, and tuberculosis in the context of lung degeneration. It is suggested that lung tissue can be restored by transplanting induced pluripotent stem cells (iPSCs) that resemble alveoli and airways. This model is recommended for drug testing, and addressing lung and liver degeneration, it may help improve the treatment of chronic obstructive pulmonary disease (COPD). To address the lack of donor organs, researchers are also looking into 3D bioprinting to create artificial lungs or lung components for transplantation.

Environmental Aspects: Inhaling Clean Air to Promote Respiratory Health

Ensuring a healthier environment for respiratory patients requires investigating green technologies, supporting clean air initiatives, and creating intelligent living environments that reduce respiratory triggers.

Healthcare professionals can use environmental data to personalize recommendations for patients, assisting them in avoiding potential triggers and better managing their respiratory conditions as more advanced sensors and monitoring devices are developed.

Ethical and Regulatory Aspects: Juggling Innovation and Accountability

Addressing ethical and regulatory issues as personalized medicine and AI integration transforms the respiratory care landscape is critical. Nailing the ethical problems posed by these developments requires maintaining transparency in AI algorithms, protecting data privacy, and striking a balance between innovation and patient safety. Building trust between patients and healthcare professionals will require the creation of clear protocols for handling patient data and the development of standardized guidelines for the moral application of AI in respiratory care.

The ethical implications of applying artificial intelligence (AI) to respiratory care demand a thorough analysis of the risks and difficulties involved. Although the merging of technology and healthcare holds great potential for progress, it also raises moral questions that affect medical AI’s dependability and credibility.

Challenges and Barriers in Respiratory Care

Respiratory care, while advancing rapidly, faces a spectrum of challenges and barriers that demand attention and innovative solutions. The challenges encompass a range of issues, such as:

  • Algorithmic bias perpetuates health disparities,
  • Unstructured medical data affecting algorithm quality,
  • Opaque algorithms undermining trust,
  • Possible hazards to patient autonomy.

Other challenges include:

  • The increasing prevalence of respiratory diseases,
  • Increased strain on healthcare systems and resources,
  • Keeping up with the technological advancement to avoid integration barriers,
  • Affordability and accessibility issues limiting access to healthcare,
  • Fragmented healthcare hinders seamless communication.

While regulations concentrate on risk management, algorithm transparency, and data quality, legal frameworks must define accountability. In the quickly changing field of medical AI, international cooperation is crucial for a comprehensive and globally applicable ethical governance system. [6]

Bringing Respiratory Care to Life

There are a lot of fascinating opportunities for respiratory care in the future. AI, biotechnological developments, personalized medicine, and an emphasis on environmental factors can transform how we diagnose and treat respiratory diseases thoroughly. It’s critical to negotiate the ethical, legal, and financial terrain as we enter this uncharted area to ensure that these innovations result in better outcomes and a breath of fresh air for patients in need.

In the future of ICUs, Artificial Intelligence is changing the game. It’s not just a trend; it’s a big step forward for better and more precise care, making critical care even more advanced and effective.

Introducing the Biyovent ICU Ventilator

A revolutionary advancement in respiratory care. What sets Biyovent apart are its exceptional specifications, meticulously crafted to elevate the ventilation process to unprecedented heights. Every aspect of Biyovent has been carefully considered and developed with a holistic approach, ensuring a comprehensive solution for optimal patient care.

In a strategic collaboration with industry leaders Arçelik, Baykar, and Aselsan, Biyovent is not only the result of cutting-edge innovation but is also poised for streamlined mass production. This partnership underscores a commitment to delivering state-of-the-art technology, setting a new benchmark in ventilator design and functionality.

Experience the future of respiratory support with Biyovent ICU Ventilator – where precision meets performance, and healthcare reaches new horizons.

References

[1] Critical Care Therapy and Respiratory Care Section (CCTRCS) | Clinical Center Home Page. (n.d.).: https://www.cc.nih.gov/ccmd/services/cctrcs.html#:~:text=Intensive%20Care%20Unit%3A,to%20most%20critically%20ill%20patient.
[2] Honkoop, P., Usmani, O., & Bonini, M. (2022, April 26). The Current and Future Role of Technology in Respiratory Care. Pulmonary Therapy; Adis, Springer Healthcare. https://doi.org/10.1007/s41030-022-00191-y 
[3] Hosny, A., Parmar, C., Quackenbush, J., Schwartz, L. H., & Aerts, H. J. (2018, May 17). Artificial intelligence in radiology. Nature Reviews Cancer; Nature Portfolio. https://doi.org/10.1038/s41568-018-0016-5
[4]Applications of AI, Machine Learning, Computational Medicine, and Bioinformatics in Respiratory Pharmacology. (n.d.). Frontiers. https://www.frontiersin.org/research-topics/58254/applications-of-ai-machine-learning-computational-medicine-and-bioinformatics-in-respiratory-pharmacology 
[5] Mahla, R. S. (2016, January 1). Stem Cells Applications in Regenerative Medicine and Disease Therapeutics. International Journal of Cell Biology; Hindawi Publishing Corporation. https://doi.org/10.1155/2016/6940283 
[6]Zhang, J., & Zhang, Z. (2023, January 13). Ethics and governance of trustworthy medical artificial intelligence. BMC Medical Informatics and Decision Making; BioMed Central. https://doi.org/10.1186/s12911-023-02103-9

mechanical-ventilation-and-ICU-ventilators

Mechanical Ventilation and ICU Ventilators: Learn All Details

Mechanical ventilation and ICU ventilators are critical components in the management of patients with severe respiratory conditions. Understanding their functionality and application is essential for effective patient care. These technologies play an important role in supporting and stabilizing patients in critical conditions.

What is Ventilation? 

ICU Ventilation is the process of movement of air from the atmosphere through the airways to the terminal respiratory gas exchange units by the effort of the respiratory muscles or mechanical ICU ventilators if the patient is being ventilated. 

What is Respiration? 

Oxygen is essential for life. It is required by each human cell for its survival. It is abundantly present in the atmosphere and maintains a remarkably constant concentration of 20.9% in ambient air. Oxygen is taken up by the lungs through the act of inspiration and transported to the cells via the blood.

At the cellular level, oxygen is utilized for the production of energy. In this process, carbon dioxide is released and transported back via the blood to the lungs from where it is expired out into the atmosphere. The act of the exchange of oxygen and carbon dioxide is called respiration. 

What is the Difference Between ICU Ventilators and Respirator? 

A ventilator is a machine, a system using mechanical power and having several parts, each with a definite function and together performing a particular task. The task here is to provide all or part of the body’s work that is called breathing or ventilation. Respirator is an apparatus that people worn it over their mouth and nose or the entire face to prevent the inhalation of dangerous substances such as: dust, smoke, etc

Indications for Ventilation

Patients who require ventilatory support often develop a common pattern of physiological deterioration, including:

  • changes in respiratory rate
  • asynchronous respiratory pattern
  • changes in mental status and changes in level of consciousness
  • frequent oxygen desaturation despite increasing oxygen concentration
  • hypercapnia and respiratory acidosis
  • circulatory problems, including tachypnea, tachycardia, hypertension, or hypotension.(3)

What is Non-invasive Ventilation (NIV)?

NIV refers to the provision of respiratory support without direct tracheal intubation. As such, it aims to avoid some of the complications inherent with invasive ventilation, such as the need for sedation with risks of hemodynamic instability and subsequent risk of delirium, nosocomial infection, etc.(2)

Recommendations for the use of non-invasive ventilation(4):

  • COPD exacerbations
  • Facilitation of weaning/extubation in patients with COPD
  • Cardiogenic pulmonary edema
  • Immunosuppressed patients
  • Do-not-intubate status
  • End-stage patients as palliative measure
  • Extubation failure (COPD or congestive heart failure) (prevention)
  • Community-acquired pneumonia in COPD
  • Postoperative respiratory failure (prevention and treatment)
  • Prevention of acute respiratory failure in asthma

Goals of Mechanical Ventilation

One of the most important treads of life support in the emergency department is Mechanical ventilation (MV). It provides time for recovery until the patient’s physiological balance is restored. This is why MV alone is not a unique and specific treatment for a particular disease; however, it has two general and main purposes: to support the injured lung and to protect the healthy lung.

Specific Goals of Mechanical Ventilation

  • Reversal of Apnea
  • Reversal of Respiratory Distress
  • Reversal of Severe Hypoxemia
  • Reversal of Severe Hypercapnia
  • Goals of Mechanical Ventilation in Postoperative
  • Respiratory Failure and Trauma
  • Goals of Mechanical Ventilation in Shock

One of the specific goals of MV is to promote the optimization of arterial blood gas levels and acid-base balance by providing oxygen and eliminating carbon dioxide (ventilation).(1) For patients with chronic diseases MV can reduce the work of breathing by taking effort from respiratory muscles and maintaining long-term respiratory support.
The ventilator is not a magical therapy that makes patients better but simply a supportive therapy used until more definitive therapies have time to work.

Apnea

Patients with apnea, such as those who have suffered catastrophic central nervous system (CNS) damage, need the immediate institution of mechanical ventilation.(2)

Indications and Contraindications for Non-invasive Ventilation

Recognizing when and when not to use NIV is crucial for its effective application. Below, we have explained the indications and contraindications for non-invasive ventilation for you

Indications (3)

  • Moderate to severe dyspnoea
  • Tachypnoea (>25–30 breaths/minute)
  • Signs of increased work of breathing (abdominal paradox; accessory muscle use)
  • Fatigue
  • Acute-on-chronic respiratory failure: pH <7.35; pCO2 >6
  • Hypoxaemia (use with caution): paO2/FiO2 <27 Kpa

Contraindications (3)

  • Facial burns/trauma/recent facial upper airway surgery
  • Vomiting
  • Upper gastrointestinal surgery
  • Copious respiratory secretions
  • Severe hypoxemia
  • Hemodynamically instability
  • Severe co-morbidities
  • Confusion/agitation
  • Low Glasgow coma score
  • Unable to protect the airway
  • Bowel obstruction
  • Respiratory arrest

NIV today consists almost exclusively of the delivery of positive pressure ventilation via an external interface. There are six broad types of interfaces available;

  • total face masks (enclose mouth, nose, eyes)
  • full-face masks (enclose mouth and nose)
  • nasal mask (covers nose but not mouth)
  • mouthpieces (placed between lips and held in place by lip seal)
  • nasal pillows or plugs (inserted into nostrils)
  • helmet (covers the whole head/all or part of the neck – no contact with face).(3)

What is Invasive Ventilation?

Invasive mechanical ventilation requires access to the trachea, most commonly via an endotracheal tube, and represents the commonest reason for admission to the ICU.(5)ICU Ventilators.

Large multinational surveys confirm the common indications for invasive ventilation to be:

  • coma 16%
  • COPD 13%
  • ARDS 11%
  • heart failure 11%
  • pneumonia 11%
  • sepsis 11%
  • trauma 11%
  • postoperative complications 11%
  • neuromuscular disorders 5%.
  • NIV contraindications.(5)

Let’s Meet with Biyovent ICU Type Mechanical Ventilator

ICU Ventilators

Biyovent ICU Type Mechanical Ventilator

ICU Ventilator of Biyovent makes a difference in the ventilation process with its unique specifications. Biyovent has been carefully thought out with every detail of the ventilators and developed with a holistic approach. Prepared for mass production in cooperation with Arçelik, Baykar, and Aselsan. ICU Ventilators

What are some specific features of Biyovent?

⦁ Invasive and Non-invasive Ventilation
⦁ Integrated Nebulizer
⦁ High Flow Oxygen Therapy
⦁ Suitable for Pediatric, Adult and Newborn (Optional) Patients
⦁ Smart Ventilation Modes

Learn more details about Biyovent ICU Ventilator

Get in contact with the Biosys Sales Team

References


1- Frank Lodeserto MD, “Simplifying Mechanical Ventilation – Part I: Types of Breaths”, REBEL EM blog, March 8, 2018. Available at: https://rebelem.com/simplifying-mechanical-ventilation-part/.
2- Tobin M.J. 3rd edn. McGraw-Hill Education; 2012. Principles and practice of mechanical ventilation.
3- Popat B, Jones AT. Invasive and non-invasive mechanical ventilation. Medicine (Abingdon). 2012;40(6):298-304. doi:10.1016/j.mpmed.2012.03.010
4- Hess D.R. The evidence for noninvasive positive-pressure ventilation in the care of patients in acute respiratory failure: a systematic review of the literature. Respir Care. 2004;49:810–829.
5- Esteban A., Ferguson N.D., Meade M.O. Evolution of mechanical ventilation in response to clinical research. Am J Respir Crit Care Med. 2008;177:170–177